Review the patient case study below and respond with explanation to…

Review the patient case study below and respond with explanation to the questions that follow

 

PATIENT CASE STUDY

Initial Presentation

• 52-year-old female diagnosed with type 2 diabetes three years ago during a work-related physical but has not followed up. 
• Presents with complaints of weakness in her right foot.

Additional History and Family History

• States left foot has been weak for a month; dorsiflexion difficult; both feet feel numb and tingly
• Noted increased thirst and urination which wakes her at night
• She has gained 20 pounds over the past year; diet is high in fats and refined sugars; nonsmoker
• Employed as a vice president in a bank; little exercise reported
• Her mother and sister have diabetes, diagnosed in their 40s; they take pills and injections
• She recalls that her blood sugar was “200ish” when she was first diagnosed, but was not worried

Lab and Diagnostic Results

• Serum electrolytes, BUN, creatinine, calcium, magnesium all normal
• Glucose (random) 250 mg/d; HgbA1c 8.5%
• Urine dipstick positive for glucose, negative for protein
• T: 37 °C orally, P: 82 regular, RR: 14 regular, BP: 162/98 right arm/sitting; weight 84 kg, height 5’4″
• Asked to return in 2 days for additional testing. 

Return visit information:

• Fasting glucose 170 mg/dl
• Fasting total cholesterol 252 mg/dl; HDL 28 mg/dl; triglycerides 652mg/dl
• Electromyography consistent with peripheral neuropathy of right foot

Medication Class

• Biguanides
• Six months later, the patient’s HgbA1c and blood glucose remain elevated, and she is started on daily insulin.

Medication

• Insulin glargine

 

QUESTIONS

 

1. What is the major cellular dysfunction contributing to the pathology of diabetes? (Provide details and credible reference)
2. Of the information listed in the patient history, laboratory, and diagnostic results, which are typical for the pathology of diabetes? Explain.
3. How does the identified class of medication relate to the pathophysiology of diabetes on a cellular level? Discuss pharmacodynamics and pharmacokinetics.
4. What will be observed to confirm a therapeutic response? Explain

Explanation & Answer

Our website has a team of professional writers who can help you write any of your homework. They will write your papers from scratch. We also have a team of editors just to make sure all papers are of HIGH QUALITY & PLAGIARISM FREE. To make an Order you only need to click Order Now and we will direct you to our Order Page at Litessays. Then fill Our Order Form with all your assignment instructions. Select your deadline and pay for your paper. You will get it few hours before your set deadline.