NU643 2022 January Week 13 Quiz Latest

NU643 Advance Psychopharmacology

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Week 13 Quiz    

Question 1First line treatment for persistent aggression is:

Select one:

 a.SSRIs

b.Anticonvulsants

 c.Atypical Antipsychotics

 d.Benzodiazepines

Question 2For which patient profile is a beta blocker a good choice the treatment of aggression?

Select one:

 a.Persistent aggression in the presence of substance abuse

 b.Acute aggression in the presence of personality disorder

 c.Persistent aggression in the presence of neurocognitive deficits

 d.Acute aggression in the presence of psychosis

Question 3The medication side effect mostly to result in aggression or violence is:

Select one:

 a.Akathisia

b. Tardive Dyskinesia

 c.Hyperreflexia

 d.Insomnia

Question 4The psychiatric disorder(s) most likely to result in aggression or violence is:

Select one:

 a.Psychotic Disorders

b.Substance Use Disorders

 c.Personality Disorders

 d.Bipolar Disorder

Question 5When prescribing for preschool aged children which of the following statements is true?

Select one:

 a.Research on the very young has led to several FDA approved medications for psychiatric disorders.

 b.SSRIs are first line treatment for depression in very young children

 c.SSRIs are first line treatment for anxiety disorders in very young children.

 d.Behavioral and psychotherapeutic interventions are first line treatment for all psychiatric disorders in preschool aged children.

Question 6When treating acute aggression, which of the following medication combinations is a suggested treatment:

Select one:

 a.Sertraline + quetiapine

 b.Propranolol + buspirone

 c.Paroxetine + Buspirone

 d.Haldol + lorazepam

Question 7Which of the following medications is FDA approved for the treatment of depression in children?

Select one:

 a.Fluoxetine

 b.Paroxetine

 c.Venlafaxine

 d.Mirtazapine

Question 8Which of the following statements about antidepressant use during pregnancy is true?

Select one:

 a.Paroxetine is considered a first line treatment for depression in pregnancy.

 b.Pharmacokinetic changes in pregnancy may result in need for higher dosages of medication to reach efficacy.

c.Treatment recommendations are consistent in their recommendation to taper SSRIs in the 3rd trimester.

 d.The evidence conclusively has drawn a link between SSRI use and development of persistent pulmonary hypertension.

Question 9Which of the following statements about antipsychotic use in pregnancy is true?

Select one:

 a.Conventional antipsychotic use for the treatment of psychosis in pregnancy is well studied.

 b.Atypical antipsychotic use in pregnancy does not appear to be associated with major congenital malformations.

c.Atypical antipsychotic use in pregnancy does not appear to be associated with withdrawal syndromes.

 d.Atypical antipsychotic use in pregnancy does not appear to be associated with increased birth weights.

Question 10Which of the following statements about antipsychotic use in the elderly is true?

Select one:

 a.Antipsychotic use in dementia is associated with increased risk of CVA and of mortality.

b.Antipsychotic use is considered appropriate in patients with Lewy Body dementia.

 c.Antipsychotic use is considered appropriate for mild aggression or agitation.

 d.Antipsychotic use in elderly patients with dementia is never appropriate.

Question 11Which of the following statements about FDA warnings and antidepressants in children and adolescents is true?

Select one:

 a.Antidepressant use has been shown to lead to an increase in completed suicides in children and adolescents.

 b.Antidepressants are contraindicated with the treatment of child and adolescent depression and anxiety.

 c.For moderate to severe anxiety and depression, antidepressant benefit may outweigh risks.

d.Untreated depression rarely has adverse long term consequences.

Question 12Which of the following statements about managing behavioral and psychological symptoms of dementia is true?

Select one:

a.Conventional antipsychotics are considered first line treatment for behavioral and psychological symptoms of dementia.

 b.Long-acting scheduled use of benzodiazepines is second line treatment for behavioral and psychological symptoms of dementia.

 c.Habilitation therapy, the practice of understanding problematic behaviors as communications of a need and then finding ways to meet that need, has been shown to reduce agitation.

d.Directive language that seeks to explain the present is the preferred communication for de-escalation.

Question 13Which of the following statements about memantine is true?

Select one:

 a.Memantine is approved for treatment of mild dementia.

 b.Memantine is a NMDA receptor antagonist and is hypothesized to reduce abnormal activation of glutamate.

c.Memantine has been shown to reduce agitation in dementia.

 d.Memantine has been shown to result in robust improvement in cognition.

Question 14Which of the following statements about neurotransmitters and development is true?

Select one:

 a.Neurotransmitter levels stay relatively constant throughout the lifetime.

 b.Serotonin levels are highest in early childhood.

 c.Norepinephrine levels increase with age.

d.Dopamine receptor sensitivity increases with age.

Question 15Which of the following statements about pediatric psychiatry is true?

a.Behavioral and psychological strategies should be included in all treatment plans.

b.Psychiatric disorders in children usually resolve without intervention.

 c.There are no significant drawbacks to withholding treatment until adulthood for most disorders.

 d.Pediatric patients respond to psychiatric medications similarly to adults but on a smaller scale.

Question 16Which of the following statements about premenstrual dysphoric disorder (PMDD) is true?

Select one:

 a.PMDD does not result in changes in level of progesterone in the luteal phase of the menstrual cycle.

 b.PMDD responds to SSRI treatment after 4-6 weeks dosing.

 c.SNRIs have been shown to be ineffective in the treatment of PMDD.

 d.Lifestyle changes such as eliminating caffeine and sugar, getting adequate sleep and regular exercise can mitigate symptoms of PMDD.

Question 17Which of the following statements about psychotropic use in pregnancy is true?

Select one:

 a.Clinicians should discuss psychotropic risks in pregnancy when a patient announces that they are pregnant.

 b.Pregnancy is protective of mental illness and most women can stop medications during pregnancy.

 c.If indicated, clinicians should choose agents that are FDA approved for use in pregnancy.

 d.All medications cross the placenta and pose a potential risk to the fetus.

Question 18Which of the following statements about SSRI discontinuation syndrome in neonates is true?

Select one:

 a.SSRI discontinuation syndrome is a relatively uncommon phenomenon in newborns exposed to antidepressant medication.

 b.Seizures and convulsions are common in SSRI discontinuation syndrome.

 c.SSRI discontinuation syndrome is time-limited and usually resolves within 2 weeks.

 d.SSRI discontinuation syndrome has lasting deleterious effects on maternal-infant bonding.

Question 19Which of the following statements and pharmacokinetics of children and adolescents is true?

Select one:

 a.The CYP450 interactions not relevant in pediatric psychiatry.

 b.Increased body fat in girls impacts distribution and half-life considerations of psychotropics when compared with boys.

c.Liver metabolism is slower in pediatric populations.

 d.Weight is not a consideration for pediatric dosing.

Question 20Which of the following statements best describes the amyloid hypothesis of Alzheimer’s?

Select one:

 a.Excessive cellular activation of glutamate leads to cell death.

 b.Abnormal processing of amyloid precursor protein results in formation of amyloid plaques and the subsequent formation of tangles.

c.ApoE activates protein kinase and leads to the formation of amyloid plaques.

 d.Acetylcholine deficiencies in the brain are linked to memory impairments.

Question 21Which of the following statements is about anticonvulsant use in pregnancy is true?

Select one:

 a.As a class, anticonvulsants carry the highest risk of major congenital malformations.

b.Among anticonvulsants, lithium poses the greatest risk.

 c.Among anticonvulsant, depakote is believed to be safest in pregnancy.

 d.Serious rash among neonates is a common occurrence with exposure to lamotrigine

Question 22Which of the following statements is FALSE when considering psychotropic medication in children and adolescents?

Select one:

 a.Risperidone is approved for acute mania in bipolar disorder.

 b.Escitalopram has been shown to be ineffective in the treatment of depression.

c.Atypical antipsychotics have been shown to reduce irritability in autism spectrum disorders.

 d.Lamotrigine requires slower upward titration than in adult populations.

Question 23Which of the following statements is true about psychotropic use during lactation?

Select one:

 a.Most medications are not secreted in breast milk.

 b.The postpartum period is considered a vulnerable time for onset, relapse and recurrence of mental disorders.

c.Infant rate of metabolism is generally similar to metabolism rates in adults.

 d.Fluoxetine and citalopram are favorable for use during lactation.

Question 24Which of the following statements is true about teratogenicity in pregnancy?

Select one:

 a.The greatest risk of teratogenicity often occurs before a patient is aware that they are pregnant.

b.Psychostimulants carry a high risk of teratogenicity.

 c.Atypical antipsychotics carry a high risk of teratogenicity.

 d.Most teratogenic risk has been determined by placebo controlled blinded studies.

Question 25Which of the following statements is true when prescribing for pediatric populations?

Select one:

 a.Adherence is generally high in pediatric populations.

 b.It is important to address parent/caregiver’s perception of psychiatric medication.

c.The meaning of taking medication is usually irrelevant to children.

 d.It is inappropriate to seek information about the patient from adults other than the parent.

Question 26Which of the following states about cholinesterase inhibitors is true?

Select one:

 a.Cholinesterase inhibitors reverse the cognitive effects of dementia.

 b.Cholinesterase inhibitors work within 4-6 weeks.

 c.GI side effects are common with cholinesterase inhibitors.

d.Cholinesterase inhibitors are most effective in late stage dementia.

Question 27Which statement best describes the mechanism of action of cholinesterase inhibitors for the treatment of dementia?

Select one:

 a.Cholinesterase inhibitors block the formation of amyloid plaques and the progression of Alzheimer’s disease.

 b.Cholinesterase inhibitors inactivate protein kinase, preventing neurofibrillary tangles.

 c.Cholinesterase inhibitors prevent the inactivation of acetylcholine, slowing the decline in function in Alzheimer’s disease.

 d.Cholinesterase inhibitors reduce abnormal activation of glutamate transmission.

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